Library / FOXO4-DRI
Mostly lab & animal studies
FOXO4-DRI
Designed "senolytic" peptide · Longevity · Proxofim
What it is
A peptide designed to make worn-out (senescent) cells self-destruct while leaving healthy cells alone.
What research covers
A 2017 study in aged mice reported improvements in fur, fitness and kidney function. There is no published human data.
Reported side effects
- No human safety data
Not suitable for, or talk to a doctor first
- Pregnancy
- Healing wounds (senescent cells play a role in healing)
- Cancer, without specialist advice
Legal status
| Australia | Not an approved medicine in Australia. Peptides like this are generally prescription-only (Schedule 4) and need a prescription to import. Check current rules with the TGA. |
|---|---|
| United States | Not FDA-approved. |
| Sport | Athletes should check the current WADA prohibited list, which changes every year. |
Rules change. Check with the TGA (Australia), your local regulator, or WADA for sport.
Key references
- Baar et al. Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging. Cell, 2017.
General information, not advice. Talk to a qualified healthcare professional before starting, changing or stopping anything.